{"id":370,"date":"2019-01-06T14:40:00","date_gmt":"2019-01-06T06:40:00","guid":{"rendered":"https:\/\/www.next-bioinfo.tw\/?p=370"},"modified":"2023-11-14T14:44:06","modified_gmt":"2023-11-14T06:44:06","slug":"%e3%80%903d-genome%e3%80%91-hi-c-%e6%9f%93%e8%89%b2%e9%ab%94%e4%b8%89%e7%b6%ad%e7%b5%90%e6%a7%8b%e6%8a%80%e8%a1%93%e5%88%86%e6%9e%90%e7%9a%84%e6%ad%b7%e7%a8%8b%e6%95%b4%e7%90%86","status":"publish","type":"post","link":"https:\/\/www.next-bioinfo.tw\/en\/2019\/01\/%e3%80%903d-genome%e3%80%91-hi-c-%e6%9f%93%e8%89%b2%e9%ab%94%e4%b8%89%e7%b6%ad%e7%b5%90%e6%a7%8b%e6%8a%80%e8%a1%93%e5%88%86%e6%9e%90%e7%9a%84%e6%ad%b7%e7%a8%8b%e6%95%b4%e7%90%86\/","title":{"rendered":"\u30103D Genome\u3011 A Brief History of Hi-C and 3D genomics technology"},"content":{"rendered":"

The following table illustrates the development and the brief history of of Hi-C and 3D genomics technology :<\/p>\n\n\n\n

ID<\/th>Publications<\/th>Chinese Translate of Publications<\/th>
DOI<\/th>		Link<\/th>Year<\/th>Milestone<\/th><\/tr><\/thead>
0<\/td>Capturing Chromosome Conformation<\/td>\u67d3\u8272\u9ad4\u7d50\u69cb\u6355\u6349(3C)<\/td>doi\uff1a10.1126 \/ science.1067799<\/td>http:\/\/citeseerx.ist.psu.edu\/viewdoc\/download?doi=10.1.1.477.3348&rep=rep1&type=pdf<\/a><\/td>2002<\/td>3-C technology was invented<\/td><\/tr>
1<\/td>Comprehensive mapping of long-range interactions reveals folding principles of the human genome.<\/td>\u5229\u7528\u9060\u7a0b\u4ea4\u4e92\u4f5c\u7528\u7684\u5168\u9762\u6620\u5c04\u89e3\u91cb\u4eba\u985e\u57fa\u56e0\u647a\u758a\u539f\u7406<\/td>doi\uff1a10.1126 \/ science.11\u200b\u200b81369<\/td>https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19815776<\/a><\/td>2009<\/td>Hi-C\u6280\u8853\u63d0\u51fa\uff0c AB\u5ba4\u7684\u767c\u73fe<\/td><\/tr>
2<\/td>Topological domains in mammalian genomes identified by analysis of chromatin interactions<\/td>\u5c0d\u65bc\u54fa\u4e73\u985e\u52d5\u7269\u67d3\u8272\u8cea\u5229\u7528\u4ea4\u4e92\u4f5c\u7528\u9032\u884c\u5206\u6790\u7528\u4f86\u5b9a\u4f4d\u62d3\u6a38\u7d50\u69cb\u57df(TAD)<\/td>doi\uff1a10.1038 \/ nature11082<\/td>https:\/\/www.nature.com\/articles\/nature11082<\/a><\/td>2012<\/td>TAD\u7684\u767c\u73fe<\/td><\/tr>
3<\/td>A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping.<\/td>\u5229\u7528\u89e3\u6790\u5ea6\u70ba\u5343\u9e7c\u57fa\u55ae\u4f4d\u7684\u4eba\u985e\u57fa\u56e0\u7d44\u4e09\u7dad\u5716\u8b5c\u89e3\u91cb\u67d3\u8272\u8cea\u74b0\u5316\u539f\u7406<\/td>doi\uff1a10.1016 \/ j.cell.2014.11.021<\/td>https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25497547<\/a><\/td>2014<\/td>LOOP\u67d3\u8272\u8cea\u74b0\u7684\u767c\u73fe<\/td><\/tr>
4<\/td>A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome.<\/td>\u5229\u7528\u67d3\u8272\u8cea\u63a5\u89f8\u5716\u6982\u7565\u5206\u6790\u4eba\u985e\u57fa\u56e0\u6d3b\u8e8d\u63a5\u89f8\u5340\u57df<\/td>doi\uff1a10.1016 \/ j.celrep.2016.10.061<\/td>https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27851967 <\/a><\/td>2016<\/td>FIRE\u71b1\u5340\u63d0\u51fa(\u9ad8\u983b\u4ea4\u4e92\u4f5c\u7528\u5340)<\/td><\/tr><\/tbody><\/table>
HiC\u67d3\u8272\u9ad4\u4e09\u7dad\u7d50\u69cb\u6280\u8853\u767c\u5c55\u7684\u91cd\u8981\u8ad6\u6587<\/figcaption><\/figure>\n\n\n\n

<\/p>\n\n\n\n

<\/p>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

\u9019\u88e1\u4ee5\u8868\u683c\u7684\u5f62\u5f0f\u6574\u7406HiC\u6280\u8853\u7684\u767c\u5c55\u6b77\u7a0b\uff0c\u6709\u8208\u8da3\u7684\u670b\u53cb\u53ef\u4ee5\u53c3\u8003\u770b\u770b \u7de8\u865f \u8ad6\u6587\u540d\u7a31 \u8ad6\u6587\u540d\u7a31\u4e2d\u8b6f DOI \u9023\u7d50 […]<\/p>","protected":false},"author":1,"featured_media":234,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-container-style":"default","site-container-layout":"default","site-sidebar-layout":"default","site-transparent-header":"default","disable-article-header":"default","disable-site-header":"default","disable-site-footer":"default","disable-content-area-spacing":"default","footnotes":""},"categories":[20],"tags":[27,37,44],"_links":{"self":[{"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/posts\/370"}],"collection":[{"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/comments?post=370"}],"version-history":[{"count":9,"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/posts\/370\/revisions"}],"predecessor-version":[{"id":379,"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/posts\/370\/revisions\/379"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/media\/234"}],"wp:attachment":[{"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/media?parent=370"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/categories?post=370"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.next-bioinfo.tw\/en\/wp-json\/wp\/v2\/tags?post=370"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}